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Software for reference genome data management.

Alpha

Refgenie v1 alpha is here. A ground-up rewrite with a built-in server, dashboard, and refget-based digests. See what’s new.

August 2026Alpha released
October 2026General availability (target)

Use refgenie with AI

Paste this into your AI agent to have it learn to use refgenie for reference genome data:

Read https://refgenie.org/SKILL.md, then use refgenie to help me with reference genome data — download and build genome assets (indexes, sequences), locate portable asset paths for my pipelines, and work with the genomes I have. The skill file teaches you the refgenie CLI and Python API.

The skill file at refgenie.org/SKILL.md teaches an assistant to operate refgenie directly. For live, read-only access to your own database, also connect the built-in MCP server — see Use refgenie with AI for both options.

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